The Expression of CD64 and CD11b Neutrophils in Neonatal Necrotizing Enterocolitis

Neonatal Necrotizing Enterocolitis

Neonatal Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) is a gastrointestinal disease that mostly affects premature infants. It involves infection and inflammation that causes destruction of the bowel. Although it affects only 1 in 2,000 to 4,000 births, or between 1 and 5% of neonatal intensive care unit admissions, NEC is the most common and serious gastrointestinal disorder among hospitalized preterm infants. We pr...

Evaluation of CD64 Expression on Peripheral Blood Neutrophils for Early Detection of Neonatal Sepsis

Background: Neonatal sepsis is a life-threatening disease with an incidence of 1 to 10 per 1000 live births and a mortality rate of 15% to 50%. The clinical signs are non-specific and indistinguishable from those caused by a variety of neonatal noninfectious disorders. Objective: The aim of this study was to determine the importance of CD64 expression (FcgRI), a neutrophil surface marker, in ea...

Neonatal Necrotizing Enterocolitis: Radiological Manifistations

Objective: The aim of this study is to determine the characteristics radiological manifestations and risk factors in neonates with necrotizing enterocolitis (NEC). Methods: A prospective study over on year starting from January 2008, conducted on 55 neonates with suspected NEC admitted at Children Hospital, Cairo University. Serial X-ray for all neonates were done and assessed Results: 31 (56.4...

Haematological abnormalities in neonatal necrotizing enterocolitis.

OBJECTIVE Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in preterm infants born prior to 32 weeks gestation or with a birth weight less than 1500 grams. In this article, we review hematological abnormalities associated with NEC. METHODS A literature search was performed using the databases PubMed, EMBASE, and Scopus, and the electronic archive of abstracts pres...